BACKGROUND: Surface waters of aquatic environments have been shown to both evolve and consume hydrogen and the ocean is estimated to be the principal natural source.In some marine habitats, H(2) evolution and uptake are clearly due to biological activity, while contributions of abiotic sources must be considered in others.Until now the only known b
Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders
AIMS OF THE STUDY Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients.The aim of this study was to qualitatively investigate reasons for trial discontinuation due to poor patient recruitment and suggesti